SmartRocker Bioreactor Systems

Combining Finesse’s SmartRocker, SmartBag, SmartPuck and SmartReader brings next generation control and measurement to rocking bioreactor applications. A Finesse SmartRocker is controlled by either a Finesse G3Lab or G3Pro Universal Controller and Finesse TruBio® software. This turn-key package provides a complete solution for research, process development, or seed train production applications.


  • Compatible with most cell culture applications
  • Controlled environment to speed up cell growth
  • Short set-up time
  • SmartBag measures main critical process parameters
  • SmartPuck sensor is USP Class VI and ADCF
  • SmartPuck design minimizes optical sensor drift
  • Plug-and-play with G3Lab Universal Bioreactor Controllers
  • Powered by TruBio software
  • Standard Service packages
  • cGMP capable

Optimize Cell Growth

Designed for R&D and cGMP scale-up, the SmartRocker allows the user to configure the rocking motion from a smooth waveform that minimizes shear force for sensitive cell lines to an aggressive motion that maximizes oxygen transfer for robust cells having high oxygen consumption. The transition from smooth to aggressive is controllable in 4 steps.

TruFluor® SmartSensors

The Finesse SmartBag is a single-use rocker bag equipped with a SmartPuck that comprises single-use sensors for dissolved oxygen, pH, and temperature. The SmartPuck leverages the technology behind TruFluor® pH and DO in a compact assembly that is pre-calibrated using a SmartChip™ and provides accurate, drift-free, in-situ measurements. The combined pH and DO optical SmartReader™ uses advanced optical components including a large area photodiode that minimizes photo-degradation of the active pH and DO sensing elements. The SmartPuck also leverages the TruFluor® temperature 316L stainless steel thermal window for highly stable readings.

The SmartPuck is welded into the single-use SmartBag and eliminates the need for sterile connectors and their associated complications such as leakage and batch contamination. All wetted materials of the SmartPuck are USP class VI compliant and animal derived component free (ADCF) and, being identical to TruFluor®, allow direct measurement comparisons and scale-up from 10L rocker bags to 2,000L stirred-tank single-use bioreactors.

The TruFluor® transmitters that are located in the utility tower will automatically read the SmartPuck calibration from the SmartChip that is embedded in it. These transmitters allow one- and two-point calibrations as well as diagnostics for sensor health and cable connectivity.


Our unique, patent-pending port-puck assembly process allows the SmartPuck to be welded to the center of the bottom of the bag. The placement and the design of the puck enable all of the sensors to remain submerged in the liquid even for small operating volumes, which results in a high degree of measurement fidelity for real time monitoring and process control. SmartRockers can therefore be utilized as a cGMP bioreactor instead of being confined to only cell amplification functions.

The SmartBag bio-process container is currently available in three (3) sizes: 10, 20, and 50 Liters. Each bag is delivered with all relevant certificates and conforms to USP Class VI standards. SmartBags come in a single, standard configuration for each volume. Please contact your Finesse representative if you require customizations for these bags.

SmartBags are manufactured using multi layer polyolefin-based, slip agent free film. This film provides superior extractables and leachables profiles, water vapor and oxygen barriers and complete fluid integrity.

SmartBags are sterilized using gamma radiation (25 to 40 kGy). Individual radiation indicators are affixed to each bag. Lot radiation information can be provided upon request. Each lot is tested for bacterial endotoxins. Lot release requires endotoxin levels below 0.125 EU/ml.

SmartRocker Trays

The tray which holds the bag and sensors is designed such that the SmartReader is mounted underneath the bag and will not disturb or encumber the rocking motion.

SmartRocker features make
starting your process quick and simple

EasyClip tray latches reduce the time required to fasten the Smartbag to the rocker and securely hold the bag inside the tray, even when it is full and the rocker is set to the most aggressive motion setting

The EasyClip lock on the SmartReader provides a repeatable and tight coupling between the SmartReader and the SmartPuck.

These features are designed to allow a very short set-up time and to establish a consistent contact between the bag and the tray for uniform heating and improved process temperature control.

Finesse SmartControllers

Choose the preferred control platform (DeltaV or µC) based on your application. In both cases, complicated programming is not required in order to create a process flow using Finesse TruBio® software. Finesse will provide full support for system configuration, documentation, and / or validation.

Choose the most appropriate controller hardware: G3Lab Universal for labscale environments or G3Pro Universal for production environments. Both controllers are fully plug-and-play with the SmartRocker and will auto-detect the rocker once it is connected to the utility tower.

SmartRocker Bioreactor

Dimensions (H x W x D) 264 x 782 x 701 mm (10.4 x 30.8 x 26.6 in)
Weight (Base + Tray) 38.5 kg (85 lbs)
Rocking Angle 2° to 12° Per Side
Rocking Rate 2 to 40 Cycles Per Minute
Working Volume (L) 5, 10, 25
Electrical Power

110 to 120 V/ 220 to 240 V, 50/60 Hz
Powered by G3 Lab Universal

Operating Temperature 0°C to 45°C (32° to 158°F)
Storage Temperature -40°C to 70 °C / -40°F to 158°F
Humidity <95%, non-condensing
Acoustic Noise Level <70 dB A
pH sensor range (pH units) 5.5 to 8.5
pH sensor relative accuracy ±0.05 pH over calibration range after a 2-point calibration having 0.3 to 0.8 pH units of separation
DO sensor range (%Sat) 0% to 250%
DO sensor limit of detection 0.03% O2
Accuracy @25 °C: <±1% at 20.95% O2
Temperature 10°C to 45°C (50° to 113°F)
Temperature accuracy ±0.15°C @ 15°C to 40°C (±0.25°F @ 59° to 104°F)
Precision ±0.1°C (±0.2°F)

G3Lab Universal Controller


Utility Tower (H x W x D) 438.4 x 250 x 482.6 mm (17.3 x 9.5 x 19 in)
Tower Rating NEMA 2
Operating Temperature 5ºC to 40ºC (41ºF to 113ºF)
Storage Temperature -40ºC to 70ºC (-40ºF to 158ºF)
Relative Humidity 5% to 95% (non-condensing)
Certifications Verified to meet CE standards EN-60101 and EN-61325
Weight / Shipping Weight 14 kg / 21.4 kg (31 lb / 47 lb)


Agitation • SmartMotor Controller – Glass Vessel or Rocker
• Vessel Adapter Box Connection – Thermo Scientific
   HyPerforma™ SUB only
• Serial Port Connection to GE Wave™ Rocker – EHT
   Model only
pH (Up to 2 inputs) TruSens Transmitter (electrochemical sensors ) or TruFluor® pH Transmitter (Rocker, Single-Use Vessel)
Dissolved Oxygen (DO) (Up to 2 inputs) TruSens Transmitter (Electrochemical Sensors ) or TruFluor® DO Transmitter (Rocker, Single-Use Vessel)
Temperature TruSens Transmitter (RTD) or TruFluor® (rocker)
Foam Level Conductivity Input
Liquid Control Four (4) Variable-Speed Peristaltic SmartPumps, Watson Marlow® Series 114 
Cold Finger Solenoid Digital Solenoid Valve
Gas Control

Standard: Four (4) MFCs with Two (2) Output Connectors

Optional: Six (6) MFCs with Three (3) Output Connectors

Scales / Load Cells Analog Input Via Scale Port
Auxiliary Seven (7) Analog Inputs and Four (4) Analog Control Loops
Digital Input Two (2) 24V DC
Digital Output Two (2) Dry-Relay Contacts

Hardware / Peripherals

Thermal Control Heater Blanket, Chilled Water Source
External Pumps Two (2) Watson Marlow® Pumps on a Finesse Pump Tower

Cable Types

pH K8, VP, TruFluor®
DO D4, VP6, VP8, TruFluor®
Heater IEC-5-15 Receptacle

Glass: 1L to 20L

Single-Use (SUB): 2.4L to 45L

Rocker: 10L to 50L

TruBio Software

Unify upstream process trains with user-friendly, configurable, scalable
bio-process software.

SmartRocker Systems

Configurable rocker motion combined with the unique SmartPuck to revolutionize rocked cell culture.