Control Vessels from Any Vendor

The G3Pro Universal controller is a complete, self-contained
bioreactor controller for bioreactors from 50L to 2,000L.

The controller leverages Finesse technology including SmartParts,
TruBio® software, and SmartSensors to enable easy cell culture
and manufacturing.

The modular design allows the G3Pro Universal to evolve with
the process and integrate 3rd-party peripherals as needed.



  • Control most any brand / size of vessel
  • cGMP-compliant hardware for large single-use bioreactors
  • Modular and Flexible
  • Available Sensor Tridundancy
  • NEMA 12-Rated Enclosure
  • Powered by TruBio® Software
  • Utilizes Finesse SmartParts Components

Compatible vessels

Bioreactor Type


Working volume (L)


Thermo Scientific
HyPerforma™ SUB

All Sizes ≤ 2000


Thermo Scientific
HyPerforma™ SUF

All Sizes ≤ 300


GE / XCellerex XDR™

All Sizes ≤ 2000


Millipore Mobius

All Sizes ≤ 200


Pall PadReactor®

All Sizes ≤ 1350


Sartorius STR®

All Sizes ≤ 1000



Utility Tower Dimensions
(H x W x D)
914.4 x 609.6 x 228.6 mm (36 x 24 x 9 in)
Cart Dimensions
(H x W x D) (Stand alone mounting cart with wheels)
178 x 71 x 81 cm (70 x 28 x 32 in)
Enclosure Rating

NEMA 12/IP54 or optionally NEMA 4X/IP65

Operating Temp 5°C to 40°C (41°F to 104°F)
Storage Temp -40°C to 85ºC (-40°F to 185ºF)
Relative Humidity 5% to 95% non-condensing
Certification Tested and verified as meeting CE Standards
EN-61010 and EN-61326
Weight / Shipping Weight 18.1 kg / 41 kg (40 lbs / 90 lbs)
Cart Weight* 75 kg (165 lbs)


Agitation Depends on Vessel Manufacturer,
Control Through VAB (Vessel Adapter Box)
pH (Up to 3 Inputs) TruSens Transmitter (Electrochemical),
TruFluor® pH Transmitter (Single-Use)
DO (Up to 3 Inputs) TruSens Transmitter (Electrochemical),
TruFluor® DO Transmitter (Single-Use)
Temperature TruSens Transmitter (RTD) and/or
TruFluor® pH/DO Transmitters (Single-Use)
Pressure TruTorr Transmitter (Single-Use)
Liquid Control Four (4) Variable-Speed Peristaltic SmartPumps,
Watson Marlow® Series 114, 313, or 520
Gas Control (TruFlow)

Standard: Six (6) MFCs with Three (3) Output Connectors

Optional: Four (4) MFCs with Two (2) Output Connectors

Scales / Load Cells Analog Input on Vessel Adapter Box
Auxiliary Eight (8) Analog Inputs and
Four (4) Analog Control Loops
Digital Output Two (2) 24V outputs; One (1) Dry Relay Alarm Contact

Cable Types

pH K8, VP, TruFluor®
DO D4, VP6, VP8, TruFluor®
Heater Cable specific to heater connected at VAB
(Vessel Adapter Box)

Hardware / Peripherals

Thermal Control Heater Blanket or Chilled Water Source
(up to 250 L vessel) Thermal Control Unit (TCU)
for Jacketed Vessels
External Pumps Watson Marlow (Series 100, 300, 500 or 600)
on SmartPump Tower or standalone SmartPump
HMI 19in color touch screen industrial LCD, NEMA 4X, 1280 x 1024, 24-bit color, keyboard and mouse
Third Party Sensors (Analog Output) CO2 – Mettler Toledo®, Cell Density – Endress+Hauser, Cell Viability – Aber™ / Fogale, Pressure / Flow

SUBs (Single-Use Vessels)

Vessel Adapter Box (VAB) Thermo Scientific HyPerforma™ SUB:
50, 100, 250, 500, 1000, 2000 L
GE/Xcellerex XDR: 50, 200, 500, 1000, 2000 L
ATMI PadReactor: 25, 50, 600, 1350 L
Millipore Mobius CellReady: 50, 200 L
Sartorius STR: 50, 200, 500, 1000 L
ASI™ SUB: 50, 300 L

*Note that the controller is not designed to be free-standing.  For this reason the controller is only shipped with the cart, for a combined weight of 116 kg (256 lbs)

SmartRocker System

Configurable rocker motion combined with the unique SmartPuck to revolutionize rocked cell culture.